Now customize the name of a clipboard to store your clips. Procedures Aida1983. Spleen Definition. The spleen plays important roles in regard to red blood cells (erythrocytes) and the immune system. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. The spleen. Grossi, P.M. Lydyard, in Encyclopedia of Immunology (Second Edition), 1998. Tuftsin binds to specific receptors on the surface of macrophages and polymorphonuclear leukocytes, stimulating their migration, phagocytic, bactericidal, and tumoricidal activity. Bone marrow is the soft, flexible connective tissue within bone cavities. the spleen is secured by four suspensory ligaments ; 1-the gastrosplenic, which connects the stomach to the spleen. Thus, the spleen is situated between the fundus of the stomach and the diaphragm. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Presentation Summary : The Spleen Anatomy of Spleen White Pulp Spleen Structure The white pulp is circular in structure and is made up mainly of lymphocytes. The peritoneum is closely adherent to the outside of the capsule. 2- Stores the breakdown products of RBCs site of erythrocyte production in the fetus. It also plays a role in both cell-mediated and humoral immune responses. Location and Structure of Spleen: Spleen lies in between the fundus of the stom­ach and the diaphragm. Schema of a venous sinus located in the cords of the red pulp. Looks like you’ve clipped this slide to already. The Spleen Anatomy Of Spleen White Pulp Spleen Structure The White PPT. The stress fibres run along the long axis of the endothelial cells and are most prominent where the endothelial cells are in contact. The spleen is encased in a thick connective-tissue capsule. The spleen can become enlarged as a result of infection, anemia or cancer. The spleen is an organ found in virtually all vertebrates.Similar in structure to a large lymph node, it acts primarily as a blood filter.The word spleen comes from Ancient Greek σπλήν (splḗn)..
It’s protected by the rib cage. Open splenectomy: incision of phrenicocolic ligament. No public clipboards found for this slide. In the adult, the spleen functions mainly as a blood filter, removing old red blood cells. Looks like you’ve clipped this slide to already. • Part of mononuclear phagocyte system. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. Structure of the spleen. The mesenchymal cells differentiate into the parenchymal cells, connective tissue and the surface capsule. The WP is the primary immunologic region of the spleen in both species; however, the WP makes up less than a quarter of splenic tissue. If you continue browsing the site, you agree to the use of cookies on this website. This is pain that the patient feels somewhere other than where the injury is located. See our Privacy Policy and User Agreement for details. The spleen is an organ located in the upper left abdomen, and is roughly the size of a clenched fist. All the efferents pass into the intestinal lymph trunks, which then enter the cisterna chyli or the abdominal confluence of lymph trunks. The largest lymphoid organ , it sites of lymphocyte proliferation and … As blood enters the abdominal cavity, it can lead to a symptom known as referred pain. Clipping is a handy way to collect important slides you want to go back to later. C.E. A considerable amount of literature has accumulated since that time, in which the authors dealing with different classes of Vertebrata, and even those who have studied the question in the same animals, have arrived at widely differing conclusions. Learn about its function, location in the body, and conditions that can affect the spleen. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. It functions in a manner. The spleen is divided by function and structure into the red pulp (RP) and white pulp (WP); in between these two regions is the marginal zone (MZ) in rodents and the perifollicular zone in humans (1, 2). The spleen is located in the upper-left part of the abdomen. Germinal centre Bcells are surface IgD2, while mantle zone B cells coexpress IgM and IgD. If you continue browsing the site, you agree to the use of cookies on this website. See our Privacy Policy and User Agreement for details. Spleen is located in left upper part of abdomen or hypochondrium. 1- Cleanses the blood by removing old RBCs and platelets, as well as debris from the blood. 2-the splenorenal, which connects the spleen to the kidney. Enlargement of the spleen is treated by addressing the underlying illness. See our User Agreement and Privacy Policy. The spleen is an organ shaped like a shoe that lies relative to the 9th and 11th ribs and is located in the left hypochondrium and partly in the epigastrium. In humans, up to a cup (236.5 ml) of red blood cells can be held in the spleen and released in cases of hypovolemia. If you continue browsing the site, you agree to the use of cookies on this website. The spleen functions as a hematopoietic center until late fetal life. The spleen is soft, highly vascular and dark purple in colour. The spleen is a small organ, typically located on the left side of the body, behind the ribcage and stomach.It is the largest organ in the body’s lymphatic system, which is responsible for promoting immune function, filtering the blood, and managing blood volume.. View and Download PowerPoint Presentations on function and Structure of GB fundus -Ant ant.abdominal... Roles in regard to red blood cells can be stored in the body, to... Half of the capsule beneath the left half of the stom­ach and the diaphragm to... Production in the fetus infection, anemia or cancer 2005 are you getting to! 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